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Article ID 3996
Title of the Article/ Research work PRELIMINARY EVALUATION OF EXTRACTS OF ALSTONIA SCHOLARIS BARK FOR IN VIVO ANTIMALARIAL ACTIVITY IN MICE
Journal Journal of Ethnopharmacology | Year : 1990 | Volume : 29 | Issue : 01 | Page : 51-57
Author(s) Gandhi M, Vinayak VK
Designation & Institution Department of Experimental Medicine, Postgraduate Institute of Medicinal Education and Research, Chandigarh, India.
Corresponding address Vinayak VK, Department of Experimental Medicine, Postgraduate Institute of Medicinal Education and Research, Chandigarh, India.
Disease related
(if any)
MALARIA(ICPC-A73|ICD-B50, B51, B52, B53, B54)
Keywords Alstonia scholaris, anti malarial, alstonine, Plasmodium berghei
Full Paper URL http://www.sciencedirect.com/science/article/pii/037887419090097D
   
Abstract / Details / Synopsis
The petroleum either extract and methanol extract of the bark of Alstonia scholaris were found to be devoid of antiamalarial activity in mice infected with Plasmodium berghei. However, a dose-dependent improvement of conditions and delayed mortality amongst animals receiving methanol extract of A. scholaris was noticed. Studies with A. constricta and alstonine shall help resolve the antimalarial status of the bark in question.